“The immune system is divided into two major classes: Cellular immunity, located in the mucous membranes of the respiratory and gastrointestinal tracts and their respective lymph nodes, and humoral immunity, with production of antigen-specific antibodies by plasma cells in the bone marrow. For eons of time the mucous membranes of the respiratory and gastrointestinal tracts have been the primary sites of microbe exposure and entry into the body, so that cellular immunity has evolved as the primary immune defense system of the body, with humoral immunity playing a secondary or backup role.
In the main, the cellular system acts through the process of phagocytosis, which involves engulfing and destroying microorganisms and cellular debris, while the antibody-producing humoral system produces antibodies in the forms of opsonins (enhance phagocytosis), agglutinins (cause agglutination or clumping), precipitins (cause an insoluble complex), and bacteriolysis (to break up). Selected samples from the medical literature indicate that the cellular immune system normally plays a primary or governing role in control of viral and fungal infections.
Generally the cellular and antibody-producing systems are complementary and interdependent. Both cellular and humoral immunities are governed by thymus-helper- lymphocytes (TH lymphocytes), the “T” referring to the thymus gland from which they are derived and the “H” referring to helper activity. Early in life uncommitted or “naïve” TH lymphocytes are differentiated into either armed TH1 cells, which govern in cellular immunity, or TH2 cells, which govern in humoral immunity. It has been found that this differentiation has been profoundly affected by cytokines, which are produced by lymphocytes and which serve as chemical messengers.
The two cytokines, interleukin 12 and interferon gamma promote and govern TH1 cells of cellular immunity, while interleukins 4, 5, 6, and 10 promote and govern TH2 cells of humoral immunity. To repeat, once one subset becomes dominant, it is difficult to shift the response to the other subset, as the cytokines from one tend to dominate the other. It necessarily follows that all current injectable vaccines, while bypassing the cellular immune system, are directed toward stimulating the inner or humoral system. This is the key to understanding the route vaccines take when injected into the human body. Furthermore, this will tend to establish the humoral system in relative dominance over the cellular system, entirely the reverse of the natural immunologic scheme that humans evolved with. This in turn results in a viral suppression of interleukin 12, on which the cellular system is largely dependent.
Consequently, current childhood vaccine programs may, in a sense, be turning childhood immune systems inside out, with the humoral system being thrown into a dominant position for which it is physiologically unsuited.
The cellular immune system, in contrast, lacking the challenges of the so-called “minor childhood diseases” of former times (measles, mumps, chickenpox, and rubella), may be going through progressive atrophy from disuse of normal physiological processes. It is true that there are many forms of viral challenges today, but only measles, mumps, rubella, and chickenpox of former pre-vaccine times challenged and therefore strengthened the immunity of both epithelial and endothelial tissues of the body and their associated organs.”
— Harold E. Buttram, MD