“The scientific literature relied upon to discredit thimerosal risks contain serious flaws in trial design and the quality of science. When the father of the modern pro-vaccine ideology, Dr. Paul Offit, goes on the attack to condemn anyone who would suggest a thimerosal-autism association, it is difficult for a rational, objective person to take him seriously.
None of the most commonly cited twenty-plus primary flagship studies referenced to discredit thimerosal risks is a biological study. Instead each is either an ecologic or cohort report. Most of these studies have been independently reviewed and trashed for gross bias, serious design flaws and scientific negligence.
The chief author of the ever-popular Danish thimerosal-autism survey is under criminal investigation for embezzling vast funds from the CDC to finance the study. A review of the Danish study’s collection methods reveals immediately it was a complete sham. Since these studies are only statistical analyses using a variety of massaged parameters to compare select populations or sub groups within a population, they are highly predisposed to intentional design defects and data manipulation in order to reach a desired result.
For this reason ecologic and cohort studies are politically desirable within the vaccine industry and the CDC. Data can be massaged in numerous ways to reach a chosen conclusion. However, in the real world of hard science, such observational, non-biological studies lack the methodological rigor to establish trustworthy scientific assumptions. In fact, the only conclusion we can draw from the arsenal of studies cited incessantly by the deniers of thimerosal’s neurotoxicty is that more comprehensive and rigorous research is demanded.
This is not to say that all ecologic and cohort studies are worthless. There are also many important cohort studies showing a vaccine-autism relationship. Some of these also suffer from poor design. Nevertheless, population studies are inconclusive and should never be used as substantial proof nor the final word to posit nor negate biomolecular activity and adverse effects of any toxic chemical or substance.
Only double-blind, placebo controlled biologic research can determine a probable medical certainty.”
— Richard Gale and Gary Null